Gene Page:

• Server displays all the records when user clicks on Gene menu. User can further filter records using Search functionality.

• Next to "Search" button, "Navigation panel" with four buttons is present. User can navigate through all the pages by clicking these four buttons.

• User can sort all the records by Gene,DER,Disease and GAD by clicking on the column header.

• System displays the order of sorting with an arrow.

• User can search by Gene Symbol or keyword for disease name.

• Enter Gene symbol or keyword in search input box. Select type of input from drop down box. Click on "Search" button.

• Default option for search functionality is Search by Gene Symbol.

• Note that, although input for search functionality is not case sensitive but user should provide full name for Gene Symbol. e.g."RunX1" or "runx1" but not "Run" or "run"

• Search by disease keyword allows user to enter keyword or part of keyword/disease name. e.g. "neuro"

• Search by description keyword allows user to enter keyword or part of keyword/description. e.g. "receptor"

• User can click on individual Gene Symbol to get gene information from NCBI's Gene database.

• User can click on GAD id to get information from Genetic Association database.

• User can click on DER value to submit relative Gene ID to Bindingene server with default q value - 0.05.

Prediction Page:

• Server displays all the records when user clicks on Prediction menu. User can further filter records using Search functionality.

• Next to "Search" button, "Navigation panel" with four buttons is present. User can navigate through all the pages by clicking these four buttons.

• User can sort all the records by Disorder,Loci,Score,Gene and DER by clicking on the column header.

• System displays the order of sorting with an arrow.

• User can search by Gene Symbol or keyword for disease name.

• Enter Gene symbol, Disorder keyword or Description keyword in search input box. Select type of input from drop down box. Click on "Search" button.

• Default option for search functionality is Search by Disorder keyword.

• Note that, although input for search functionality is not case sensitive but user should provide full name for Gene Symbol. e.g."RunX1" or "runx1" but not "Run" or "run"

• Search by disorder/description keyword allows user to enter keyword or part of keyword/disease name. e.g. "neuro"

• Search by Loci allows user to input Locus or part of Locus. e.g. "21q22"

• User can click on individual Gene Symbol to get gene information from NCBI's Gene database.

• User can click on Disorder to get information from NCBI's OMIM database.

• User can click on DER value to submit relative Gene ID to Bindingene server with default q value - 0.05.